This is the 5367th most frequent Russian word.
отпуске
"Отпуске" means "vacation" or "leave" in English.
The word 'отпуске' is in the prepositional case, indicating the location 'on vacation'.
Мы были в отпуске прошлым летом.
We were on vacation last summer.
The word 'отпуске' is used in the prepositional case as part of the prepositional construction 'об отпуске', expressing about an abstract concept.
Он мечтает об отпуске на море.
He dreams of a vacation by the sea.
Here, 'отпуске' is used in the prepositional case as part of the phrase indicating a state or location.