This is the 11140th most frequent Russian word.
госпожу
"Госпожу" means "Madam" or "Mrs." (accusative case).
The word 'госпожу' here is used as an accusative form to address or refer to a female respectfully as a part of her name.
Я видел госпожу Иванову в кафе.
I saw Mrs. Ivanova at the cafe.
The word 'госпожу' takes the instrumental form when paired with 'с' to show respect while addressing a female in a professional context.
Он хотел поговорить с госпожой директором.
He wanted to speak with Madam Director.
The word 'госпожу' is used here as an accusative form to respectfully address a female, not linked to a name, expressing gratitude or acknowledgment.