This is the 13006th most frequent Spanish word.
picarme
"To sting me" or "to bite me."
Here, 'picarme' is used to indicate that the mosquito is biting the speaker, referring to the literal act of an insect puncturing the skin.
Cuando salí al parque, un mosquito empezó a picarme.
When I went to the park, a mosquito started to bite me.
In this sentence, 'picarme' refers to causing an itching sensation, particularly in the nose.
El polvo de la habitación empezó a picarme la nariz.
The dust in the room started to make my nose itch.
Here, 'picarme' metaphorically refers to provoking or annoying the speaker through comments or actions.