This is the 11342nd most frequent Russian word.
детдома
"Детдома" means "orphanages" in English.
Here, 'детдома' is in the genitive case, indicating 'from the orphanage'.
Я видел детей из детдома, они очень дружные.
I saw children from the orphanage, they are very friendly.
In this case, 'детдома' is nominative plural, referring to orphanages in general.
Детдома нуждаются в поддержке со стороны общества.
Orphanages need support from the community.
Here, 'детдоме' is in the prepositional case, used after the preposition 'в' to indicate location in the orphanage.