This is the 1708th most frequent Polish word.
rodziną
"Rodziną" means "family" (instrumental case) in English.
Here, 'rodziną' is in the instrumental case, indicating accompaniment or association (with my family).
Spędzam weekend z rodziną.
I am spending the weekend with my family.
In this sentence, 'rodziną' is used in the prepositional case after the preposition 'o' to indicate the topic of conversation (about my family).
Często rozmawiam o mojej rodzinie.
I often talk about my family.
Again using the instrumental case 'rodziną' after 'z' to indicate accompaniment or being together with (my family).