This is the 8356th most frequent Japanese word.
微笑み
"微笑み" means "smile" in English.
In this sentence, "微笑み" (smile) is used as the subject to convey the comforting effect of someone's smile.
彼女の微笑みが私を安心させた。
Her smile reassured me.
Here, "微笑み" refers to the smile depicted or represented in the painting.
その絵には微笑みが描かれている。
The painting depicts a smile.
The word "微笑み" is positioned as the direct object, describing the smile that the person gives to another.